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WebbFirst, activation peptide of trypsinogen is under strong selection pressure to minimize autoactivation in higher vertebrates. Second, the R122 primary autolysis site has further evolved in mammalian trypsinogens. Third, evolutionary divergence from threonine to asparagine at residue 29 in human cationic trypsinogen provides additional advantage. Webb11 apr. 2024 · Kidney damage has been considered as one of the major abnormalities amongst growth retardation, anemia, skin lesions, and neurodegenerative changes when riboflavin deficiency is observed, as a result of dietary deprivation or periods of pathological or physiological stress [ 51, 52 ]. sum leafy vegetable in chinese cuisine
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