Lamp2b
Tīmeklis2024. gada 1. febr. · Plasmid CAP-lamp2b includes a glycosylation sequence (GNSTM), a E7 sequence (EPLQLKM) and glycine-serine spacers at the N-terminus of lamp2b … TīmeklisDownload scientific diagram Targeting peptide expressed with Lamp2b is expressed on the external surface of exosomes. (a) Schematic representation of production, harvest and re-administration of ...
Lamp2b
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TīmeklisPlays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the … Tīmeklis2024. gada 23. maijs · The expression of CTP-Lamp2b peptide on exosomes was stabilized by attaching glycosylation sequences. Exosomes expressing only Lamp2b …
Tīmeklis1.一种用于肿瘤放疗增敏的工程化外泌体，其特征在于，所述用于肿瘤放疗增敏的工程化外泌体外部修饰肿瘤靶向肽，内部包裹小干扰RNA核酸药物。 2.根据权利要求1所述的用于肿瘤放疗增敏的工程化外泌体，其特征在于，所述核酸药物是长度为15‑30个核苷酸。 3.根据权利要求2所述的用于肿瘤放疗增 ...
TīmeklisPlasmid pCDNAHygro(+)LAMP2B from Dr. Janice Blum's lab contains the insert Lysosome-associated membrane protein 2b and is published in Immunity. 2005 … Tīmeklis2015. gada 27. marts · Indeed, peptides fused to the N terminus of exosome-associated transmembrane protein Lamp2b were cleaved in samples derived from both cells and exosomes. To suppress peptide loss, we engineered targeting peptide-Lamp2b fusion proteins to include a glycosylation motif at various positions. Introduction of this …
Tīmeklis2024. gada 4. aug. · For example, lysosome-associated membrane protein 2b (Lamp2b) is an exosomal surface protein with an exosomal signal peptide. Fusion of a protein of interest to Lamp2b is very common for displaying the protein on the surface of exosomes as a targeting moiety, ligand, or receptor. A Lamp2b-based fusion …
Tīmeklis2015. gada 3. marts · The Lamp2b fusion proteins were expressed at similar levels in cells, as indicated by the HA Western blot. However, the FLAG peptide on FLAG-Lamp2b-HA could not be detected, although the C-terminal FLAG peptide of Lamp2b-HA-FLAG was detected (Fig. 1 E). The same pattern was observed in exosomes … adire le opportune sediTīmeklisLAC2B is a leading Global E-Commerce Distributor of Cosmetics and Health products, with door to door delivery and a transit time of 24 hours / 96 hours directly to … jreポイント 何に使うTīmeklis2024. gada 23. jūn. · lamp2基因9号外显子的剪切差异可致所编码的lamp2蛋白存在lamp2a、lamp2b及lamp2c 3种亚型，区别仅在于溶酶体羧基末端跨膜区域及胞浆短 … adire l\u0027autorità giudiziariaTīmeklis2024. gada 24. nov. · Lamp2b-HuR融合蛋白功能化的外泌体能够将被RNA结合基序识别的RNA靶标驱动至溶酶体以在受体细胞中降解。 该系统在富含溶酶体的巨噬细胞中 … adire l\\u0027autorità giudiziariaTīmeklis2011. gada 20. marts · FLAG-Lamp2b was strongly expressed in dendritic cells and was incorporated into the dendritic cell–derived exosomes based on western blots with anti-FLAG and anti-Lamp2b antibodies . As the ... adire l\u0027autoritàTīmeklisfindings indicated that patients with Danon disease caused by mutations in exon 1 - 8 manifested as a typically severe phenotype, while patients with mutations in exon 9 of the LAMP2B isoform presented with a relatively benign phenotype; A novel LAMP2 mutation (c.940delG) in Danon disease patients, which results in a putatively … adire l\\u0027autoritàTīmeklis2024. gada 8. janv. · Here, we identify the LAMP-2 isoform B (LAMP-2B) as required for autophagosome-lysosome fusion in human cardiomyocytes (CMs). Remarkably, LAMP-2B functions independently of syntaxin 17 (STX17), a protein that is essential for autophagosome-lysosome fusion in non-CMs. Instead, LAMP-2B interacts with … jreポイント 何歳から