Hemistepsin a
WebMay 4, 2024 · Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human … WebJan 1, 2024 · Hemistepsin A, a sesquiterpene lactone compound isolated from Hemistepta lyrata, has been identified a variety of pharmacological actions including anti-hepatotoxic, …
Hemistepsin a
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WebDec 17, 2024 · Rhein exerts its anti-inflammation function by regulating the PPAR-γ-NF-κB-HDAC3 axis, indicating that PPar-γ is a critical mediator in the rhein-mediated anti-inflammatory process. Inflammation is a common inducer of numerous severe diseases such as sepsis. The NF-κB signaling pathway plays a key role in the inflammatory process. Its … WebFeb 5, 2016 · Hemistepsin A (HsA) is a sesquiterpene lactone isolated from Hemistepta lyrata (Bunge) Bunge. We investigated the anti-inflammatory effects of HsA and sought to determine its mechanisms of action in macrophages. HsA pretreatment inhibited nitric oxide production, and reduced the expression of iNOS and COX-2 in Toll-like receptor ligand ...
WebDec 1, 2024 · Hemistepsin A (HsA) inhibits cell growth and induces apoptosis in prostate cancer cells. ( A, B) Cell growth inhibition: Cell viability was assessed by 3- (4,5-dimethyl … WebApr 13, 2024 · Adenophora stricta Miq. (Campanulaceae family) is a traditional herb used for relieving cough and phlegm in East Asia. This study explored the effects of A. stricta root extract (AsE) in ovalbumin (OVA)-induced allergic asthma and lipopolysaccharide (LPS)-stimulated macrophages. Administration of 100–400 mg/kg AsE dose-dependently …
WebTwo STLs, one for which we created the trivial name ragusinin, and hemistepsin A are here reported for the first time as constituents of the genus Centaurea. All six compounds were screened for their effect on several tumor and one normal cell lines. WebHemistepsin A (HsA) is a guaianolide sesquiterpene lactone that inhibits hepatitis and liver fibrosis. We evaluated the effects of HsA on liver X receptor (LXR)-mediated hepatic lipogenesis in...
WebSansum Clinic, founded in 1921, is one of the oldest non-profit outpatient clinics in California. Located in Santa Barbara, it is also one of the largest healthcare providers on …
WebHemistepsin C19H22O6 CID 10043230 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... michael plevin yorkWebSupplementary Information . Title: Hemistepsin A inhibits T0901317-induced lipogenesis in the liver Author’s name: Jae Kwang Kim1,2,#, Il Je Cho1,#, Eun Ok Kim1, Dae Geon Lee1, Dae Hwa Jung1,3, Sung Hwan Ki4, Sae Kwang Ku1,*, Sang Chan Kim1,**. Affiliation: 1College of Medicine, Daegu Haany University, Korean Gyeongsan, Gyeongsangbuk-do … michael pleveichWebThe two hemistepsin derivatives were examined for their in vitro cytotoxic activity against human cell lines such as UACC 62, HCT 15, UO-31, PC-3 and A549. Growth inhibitory property was determined by in vitro treatment of the respective cell lines using the sulforhodamine B assay (SRB). Both compounds exhibited significant cytotoxic activity ... michael pliscoWebDec 5, 2024 · Hemistepsin A protects human keratinocytes against hydrogen peroxide-induced oxidative stress through activation of the Nrf2/HO-1 signaling pathway 2024, Archives of Biochemistry and Biophysics Show abstract Effect of Sorbus domestica and its active constituents in an experimental model of colitis rats induced by acetic acid michael plibersekWebDec 14, 2024 · Hemistepsin A (HsA) is a sesquiterpene lactone isolated from Hemistepta lyrata Bunge (Compositae). Here, we report that HsA is a PDK1 inhibitor can reduce the … michael pleacher mdWebApr 29, 2024 · Hemistepta lyrata (Bunge) Bunge is a biennial medicinal plant possessing beneficial effects including anti-inflammation, and hemistepsin A (HsA) isolated from H. lyrata has been known as a hepatoprotective sesquiterpene lactone. In this report, we explored the cytotoxic effects of H. lyrata on hepatocellular carcinoma (HCC) cells and … michael plick \u0026 associatesWeb暨南大学,数字图书馆. 开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 michael p. lee reed smith