Ferm domain-containing protein
WebThe amino-terminal region of FAK contains a region of sequence homology with band 4.1 and ezrin/radixin/moesin (ERM) proteins termed a FERM domain. FERM domains are … WebMar 21, 2024 · FERM domain–containing protein 6 (FRMD6) is a member of the FERM protein superfamily, which is evolutionary highly conserved and has recently been …
Ferm domain-containing protein
Did you know?
WebMar 21, 2024 · FERMT3 (FERM Domain Containing Kindlin 3) is a Protein Coding gene. Diseases associated with FERMT3 include Leukocyte Adhesion Deficiency, Type Iii and Leukocyte Adhesion Deficiency, Type I . Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Leukocyte-intrinsic Hippo pathway functions . WebThe β1–β2 and α2–β5 loop regions are also longer and contain 3 10 helices, a feature unique among the FERM domain-containing proteins (Ceccarelli et al., 2006). Each of …
WebMar 21, 2024 · This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014] GeneCards Summary for FRMD4B Gene FRMD4B (FERM Domain Containing 4B) is a Protein Coding gene. Web类别：FERM domain-containing proteins . Four-jointed (Fj) 功能：将Fat与Ds胞外的部分磷酸化，来影响它们的相互作用和活性。 ps Fj和Ds在果蝇翅成虫盘的表达区域是互补的。 类别：Golgi-localized kinase . Discs overgrown (Dco)
Web282-427: 1.93e-73: FERM domain C-lobe of Janus kinase 1; JAK1 is a tyrosine kinase protein essential in signaling type I and type II cytokines. It interacts with the gamma chain of type I cytokine receptors to elicit signals from the IL-2 receptor family, the IL-4 receptor family, the gp130 receptor family, ciliary neurotrophic factor receptor (CNTF-R), … WebMar 21, 2024 · The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. ... FERM domain-containing protein 3, band 4.1-like protein 4, band 4.1-like protein 4O, ovary …
WebOct 22, 2010 · Importantly, the FAK FERM domain might act as a paradigm for the actions of other FERM domain-containing proteins. Focal adhesion kinase (FAK) is a scaffold and tyrosine kinase protein that binds ...
WebSep 4, 2024 · This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein … regle du jeu dominosWebSep 9, 2024 · First, a key leucine residue (L353) in the SNX17 FERM domain involved in contacting the tyrosine in the NPxY/NxxY motif is an alanine in the SNX27 FERM … regle du jeu goWebMay 8, 2014 · The protein 4.1R, ezrin, radixin, moesin (FERM) superfamily consists of over 40 proteins all containing a three lobed N-terminal FERM domain which binds a variety of cell-membrane associated proteins and lipids. The C-terminal ends of these proteins typically contain an actin-binding domain (ABD). regle du jeu goalWebThe protein 4.1R, ezrin, radixin, moesin (FERM) superfamily consists of over 40 proteins all containing a three lobed N-terminal FERM domain which binds a variety of cell-membrane associated proteins and lipids. The C-terminal ends of these proteins typically contain an actin-binding domain (ABD). regle du jeu go popWebFeb 22, 2024 · The protein Na +, H +-exchanger 1 (NHE1) contains a positively-charged ERM-binding motif in the C-terminal cytoplasmic tail, which binds to the FERM domain of ezrin . The ERM proteins, especially ezrin, also directly bind to the P-glycoprotein (P-gp), which is a key player in multidrug-resistant phenotypes in cancer. regle du jeu go gorillaWebFERM domains are trilobed, typically N-terminal domains (Chishti et al., 1998). They are commonly found in proteins that bind cytoplasmic regions of transmembrane proteins … regle du jeu goal fdjWebThis gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014] Expression Ubiquitous expression in spleen (RPKM 7.8), esophagus (RPKM 7.0) and 25 other tissues Orthologs mouse all NEW e3 u\\u0027s