WebThe Cdh5(PAC)-CreERT2 mouse exhibits tissue-specific expression of an inducible Cre-ERT2 fusion protein, enabling tamoxifen-induced Cre recombinase activity in vascular … WebJun 18, 2024 · Treatment of eNOS flox/flox Cdh5-Cre/ERT2 pos/neg with tamoxifen induces an EC-specific Cre-mediated DNA recombination leading to excision of exon 2 in the Nos3 genomic locus to obtain EC eNOS KO (eNOS flox/flox Cdh5-Cre/ERT2 pos) or their littermate WT (eNOS flox/flox Cdh5-Cre/ERT2 neg) controls (Table 1).
MiR-126-3p Is Dynamically Regulated in Endothelial-to ... - PubMed
WebApr 14, 2024 · The following mouse strains were used (all on a C57BL/6 background): Cdh5 CreERT2:ZsGreen l/s/l mice (control mice; TgCdh5-Cre/ERT2 1Rha) and Cdh5 CreERT2:Dnmt1 fl/fl:ZsGreen l/s/l mice (Dnmt1 ... WebArticle Snippet: For the atherosclerosis lesion development studies, S1pr1 f/f Cdh5-Cre ERT2 mice were crossed with Apoe −/− mice (Jackson Laboratory) for >4 generations to … penningtons grande prairie
Functional Definition of Progenitors Versus Mature
The Tg(Cdh5-cre/ERT2) 1Rha allele has been used extensively to study the postnatal vasculature, with tamoxifen administration between P1 and P6 able to induce pan-EC Cre-mediated recombination in both retina and brain endothelium. 47,49 Tamoxifen injection at 2 weeks after birth has also been shown to produce efficient recombination in the ... WebRecombinase (cre) Nomenclature; References; Clone Collections; DNA Mapping Panels; More Resources. More Resources Index; Research Community E-mail Lists; Online Books; ... (Ccr2-cre/ERT2)12Kuan transgene insertion, Chia-Yi Kuan Driver: Ccr2 Type: Transgenic (Inducible, Recombinase) Inducer: tamoxifen Synonym: CCR2-CreER(T2) ... Web017968 B6;129-Tg(Cdh5-cre)1Spe/J These VEC-cre transgenic mice express Cre recombinase under the control of a Cdh5 promoter with greater efficiency than other … pennisetum alop. viridescens